What type of immune response may be elevated in cases of lymphoma?

In cases of lymphoma, the humoral immune response is often elevated because this type of response is associated with the production of antibodies by B cells. Lymphoma, particularly B-cell lymphoma, originates from these same B cells, which can lead to increased levels of immunoglobulins or antibodies in the serum. This response is a hallmark of various lymphoproliferative disorders, including lymphoma, where the malignant cells disrupt normal immune function and can cause dysregulation in antibody production.

The elevation in the humoral immune response can manifest through polyclonal gammopathy, where a broad range of antibodies are produced, often in an uncontrolled fashion due to the neoplastic proliferation of immune cells. This contrasts with other immune responses, such as cell-mediated immunity and innate immune response, which may not show significant changes directly related to the lymphoma's development or prevalence.

While the adaptive immune response encompasses both humoral and cell-mediated components, it is specifically the humoral aspect that is typically noted for elevation in the context of a B-cell lymphoma diagnosis, making it the most relevant option in this scenario.