Which breed has an increased risk of developing transitional cell carcinoma?

The Scottish Terrier is indeed recognized as a breed with a significantly increased risk of developing transitional cell carcinoma (TCC). This breed has been the subject of numerous studies indicating a higher prevalence of TCC compared to other breeds. Transitional cell carcinoma primarily affects the urinary bladder, and certain breeds, including the Scottish Terrier, show a genetic predisposition to this aggressive form of cancer.

Research has identified specific genetic and environmental factors associated with the breed's susceptibility. Factors such as exposure to certain chemicals (like cyclophosphamide, commonly used in chemotherapy) may also play a role, but the breed's inherent predisposition is a significant consideration for veterinarians when diagnosing and treating this condition. Early detection and breed-specific awareness can lead to more effective management and treatment strategies for affected Scottish Terriers.